产品货号：
Z37851
中文名称：
GluR4/GRM4抗体
英文名称：
Anti-GluR4/GRM4 Antibody (Clone#OTI6D1)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GluR4/GRM4 Antibody (Clone#OTI6D1) |
| 指标别名 | Glutamate receptor metabotropic 4 antibody|GPRC1D antibody|Grm4 antibody|GRM4 antibody|Metabotropic glutamate receptor 4 antibody|mGlu4 antibody|mGluR4 antibody |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | GRM4 |
| 克隆号 | OTI6D1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 126-407 of human GRM4 (NP_000832) produced in E.coli. |
| 实际分子量 | 101.87KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors.Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.The metabotropic glutamate receptors are a family of G protein-coupled receptors,that have been divided into 3 groups on the basis of sequence homology,putative signal transduction mechanisms,and pharmacologic properties.Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C.Group II includes GRM2 and GRM3 while Group III includes GRM4,GRM6,GRM7 and GRM8.Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.Several transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q14833 |
| 基因名全称 | Metabotropic glutamate receptor 4 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:500 |
相关搜索：GluR4/GRM4抗体，GluR4抗体，GRM4单抗，Anti-GluR4/GRM4 Antibody (Clone#OTI6D1)